ESPCI web site
Le séminaire hebdomadaire du laboratoire PMMH a lieu tous les vendredis à 11h, au premier étage Barre Cassan, campus Jussieu (plan).
Stéphane Perrard
Etienne Reyssat
Virgile Thiévenaz
PMMH
BARRE CASSAN
BAT A 1ER ETAGE CASE 18
7 QUAI SAINT BERNARD
75005 PARIS
France
Tel : (33) 1 40 79 45 22
Séminaire PMMH - Barakat Abdul (Ladhyx, Polytechnique)
Optimizing the Performance of Endovascular Stents : Cells, Vessels, and Connected Devices
The pathological complications of atherosclerosis, namely heart attacks and strokes, are the leading cause of mortality in the world. The most common treatment for atherosclerosis is the implantation of a stent, a wire-mesh structure that is deployed on a balloon catheter and expanded at the location of arterial obstruction to restore blood flow. Most stents deployed in coronary arteries today are drug-eluting stents (DES) that release a drug into the arterial wall in a controlled manner in order to prevent the occurrence of certain complications. However, despite the widespread use of DES, there is a persistent risk of serious complications including in-stent restenosis (vessel re-blockage), late stent thrombosis (blood clot formation), and stent fracture.
Minimizing the incidence of these complications requires devising optimal DES designs that strike a fine balance among a myriad of competing considerations including drug release dynamics, stent strut dimensions, and stent surface characteristics that accelerate device cellular coverage. In this talk, I will describe a multi-variable optimization approach to optimize DES design. I will also present a stentable coronary artery mimic that we have developed in order to experimentally test the predictions of the computational optimization. This arterial mimic contains the relevant cells of the arterial wall and allows cellular monitoring as well as detailed characterization of arterial flow fields using particle image velocimetry. Finally, I will describe two novel approaches for radically improving stent performance : 1) patterning stent surfaces to accelerate device cellular coverage, and 2) developing smart and communicating stents that can detect the onset of stent restenosis or thrombosis and communicate the information wirelessly to the outside world.
Séminaires (4)
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Séminaire PMMH - Francesca Borghi Università degli Studi di Milano
Vendredi 20 juin de 11h00 à 12h00 - Salle réunion PMMH 1
REPROGRAMMABLE HARDWARE FOR DATA PROCESSING AT THE EDGE : A NEW COMPUTING PARADIGM BASED ON NEUROMORPHIC SYSTEMS
The brain's ability to perform efficient and fault-tolerant data processing is strongly related with its peculiar interconnected adaptive architecture, based on redundant neural circuits interacting at different scales. By emulating the brain's processing and learning mechanisms, computing technologies strive to (…) -
Séminaire PMMH - Francesca Borghi Università degli Studi di Milano
Vendredi 20 juin de 11h00 à 12h00 - Salle réunion PMMH 1
REPROGRAMMABLE HARDWARE FOR DATA PROCESSING AT THE EDGE : A NEW COMPUTING PARADIGM BASED ON NEUROMORPHIC SYSTEMS
The brain's ability to perform efficient and fault-tolerant data processing is strongly related with its peculiar interconnected adaptive architecture, based on redundant neural circuits interacting at different scales. By emulating the brain's processing and learning mechanisms, computing technologies strive to (…) -
Séminaire PMMH - Salvatore Federico (University of Calgary, Canada)
Vendredi 4 juillet de 11h00 à 12h00 - Salle réunion PMMH 1
Continuum Mechanics of Hydrated Fibre-Reinforced Soft Tissues
Biological tissues can be represented as bi-phasic continua, with a porous solid phase saturated by an interstitial fluid and reinforced by collagen fibers. This lecture will give an overview of the modelling techniques for fibre-reinforced porous composite materials with statistical orientation of the fibers. Both (…) -
Séminaire PMMH - Salvatore Federico (University of Calgary, Canada)
Vendredi 4 juillet de 11h00 à 12h00 - Salle réunion PMMH 1
Continuum Mechanics of Hydrated Fibre-Reinforced Soft Tissues
Biological tissues can be represented as bi-phasic continua, with a porous solid phase saturated by an interstitial fluid and reinforced by collagen fibers. This lecture will give an overview of the modelling techniques for fibre-reinforced porous composite materials with statistical orientation of the fibers. Both (…)
Instructions générales pour les conférenciers
Le public du séminaire est très hétérogène (rien qu’au PMMH nous travaillons sur des thématiques très diverses, mécanique des fluides, des milieux granulaires, des solides, physique statistique, physique du mouillage, micro-fluidique, biophysique,...) l’objectif est donc de ne pas faire un séminaire trop spécialiste : au moins la première moitié du séminaire à un niveau accessible pour celui qui ne connaît rien sur le sujet.
Le séminaire a lieu à 11h. rendez-vous 15 minutes avant pour installer et tester la projection.
Le séminaire dure environ 45 minutes pour laisser un peu de temps pour discuter à la fin.
- Séminaires ESPCI-ENS de biophysique
- Séminaires du Département de Physique de l’ENS
- Séminaires du Laboratoire d’Hydrodynamique de l’X
- Séminaire de Mécanique d’Orsay (page web FAST)
- Séminaire de Mécanique d’Orsay (page web LIMSI)
- Séminaire de Mécanique des Fluides de l’Institut Jean le Rond d’Alembert
- Séminaires du laboratoire MSC, Paris VII
- Séminaires Gulliver
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