PMMH’s weekly seminar is held every Friday at 11 am (map)
Stéphane Perrard
Etienne Reyssat
Virgile Thiévenaz

PMMH
BARRE CASSAN
BAT A 1ER ETAGE CASE 18
7 QUAI SAINT BERNARD
75005 PARIS
France
Tel : (33) 1 40 79 45 22
Thierry Savin (ETH Zürich)
Occlusive flow of red blood cells
When red blood cells (RBCs) move through narrow capillaries in the microcirculation, they deform as they flow. In pathophysiological processes such as sickle cell disease and malaria, RBCs' deformability is altered and their motion is severely restricted. This can lead to vaso-occlusive crises with dramatic consequences. To understand the dynamics close to the threshold of occlusion, we used experiments and theory to study the motion of a single swollen RBC through a narrow glass capillary of varying inner diameter. We tracked the motion of the squeezed cell as a function of the driving pressure head and of the confinement diameter, and used a simple elasto-hydrodynamic model to explain the increase in the effective viscosity associated with the occlusion regime.
The audience is composed of people with rather heterogeneous backgrounds including specialists in solids, fluids, granular flows, statistical physics... so the idea is to keep your talk understandable by people not necessarily working in your field... The seminar time slot runs from 11am to noon so the best is to make the talk last around 45 minutes to leave some time for discussion.
- Séminaires ESPCI-ENS de biophysique
- Séminaires du Département de Physique de l’ENS
- Séminaires du Laboratoire d’Hydrodynamique de l’X
- Séminaire de Mécanique d’Orsay (page web FAST)
- Séminaire de Mécanique d’Orsay (page web LIMSI)
- Séminaire de Mécanique des Fluides de l’Institut Jean le Rond d’Alembert
- Séminaires du laboratoire MSC, Paris VII
- Séminaires Gulliver
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