Seminars

PMMH’s weekly seminar is held every Friday at 11 am (map)

Contact :
Stéphane Perrard
Etienne Reyssat
Virgile Thiévenaz
responsables-seminaires (arobase) pmmh.espci.fr

PMMH
BARRE CASSAN
BAT A 1ER ETAGE CASE 18
7 QUAI SAINT BERNARD
75005 PARIS
France

Tel : (33) 1 40 79 45 22


Séminaire PMMH – Lara Kohler (Max Planck Dresden)

Vendredi 19 décembre 2025 de 11h00 à 12h00 - Salle réunion PMMH 1

Flow–wave coupling synchronizes oscillations in growing active matter

Oscillatory biochemical signals and mechanical forces must coordinate robustly during development, yet the principles governing their mutual coupling remain poorly understood. In syncytial embryos and cell-free extracts, mitotic waves propagate across millimeter scales while simultaneously generating cytoplasmic flows, suggesting a two-way interaction between chemical oscillators and mechanics. Here, we combine experiments in Xenopu Laevis cytoplasmic extracts with a minimal particle-based model to uncover a mechanochemical feedback that stabilizes wave propagation. Particles grow slowly and shrink rapidly under cell-cycle control ; this asymmetric size cycle, together with size-dependent mechanical interactions, generates flows aligned with the phase gradient. These flows mix particles, promote neighbor exchange, and enhance phase synchronization. As a result, asynchrony generates flows, and these flows eliminate asynchrony, producing a robust transition from a flowing, disordered state to a synchronized, mechanically quiescent one. Our results show that mechanical forces do not merely perturb biochemical wave, but actively maintain their coherence, providing a general mechanism for long-range order in oscillating active matter.

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Recent seminars  (6)

Information for the speakers

The audience is composed of people with rather heterogeneous backgrounds including specialists in solids, fluids, granular flows, statistical physics... so the idea is to keep your talk understandable by people not necessarily working in your field... The seminar time slot runs from 11am to noon so the best is to make the talk last around 45 minutes to leave some time for discussion.

Link to cofee seminar (internal, every Thursday)


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Contact

Directeur : Ramiro GODOY DIANA
Codirecteur : Laurent DUCHEMIN
Administratrice : Frédérique AUGER (01 40 79 45 22)
Gestionnaire : Claudette BAREZ (01 40 79 58 53)
Courriel : dir (arobase) pmmh.espci.fr
Téléphone : 01 40 79 45 22
Adresse : PMMH UMR 7636 CNRS, ESPCI Paris-PSL, Sorbonne Université, Université Paris Cité
7 Quai Saint Bernard, Barre Cassan Bât A 1er étage Case 18, 75005 Paris